Unexplained body odor may stem from rare genetic disorder

People whose bodies or breath are foul-smelling despite their good hygiene have a frustrating lot in life: Their social lives and careers may be hindered by their fear of offending others with their odor, yet they don't know what to do to make themselves smell better.

But new research may lead to relief for some who suffer from such chronic malodor.

Researchers at the Monell Chemical Senses Center tested 353 people who had sought help in understanding and dealing with the odors their bodies produced. Through a simple test, the scientists learned that about a third of them had a rare, but treatable, genetic disorder called trimethylaminuria. People with this condition lack the enzyme required to properly metabolize trimethylamine, a substance found in many common foods.

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Greg Miller 02 Sep, 2011


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